CJC-1295 no DAC 2mg
CJC-1295 without DAC (also known as Modified GRF 1-29 or Mod GRF) is a synthetic analogue of growth hormone-releasing hormone comprising the first 29 amino acids of GHRH with four substitutions to improve metabolic stability. Unlike the DAC variant, this form has a half-life of approximately 30 minutes.
The shorter half-life of CJC-1295 no DAC produces a more physiological pulsatile pattern of GH release, which more closely mimics the body natural secretory rhythm. This property makes it particularly valuable for research into the effects of pulsatile versus sustained GH elevation and their differential downstream effects.
In research settings, CJC-1295 no DAC is frequently combined with Ipamorelin to study synergistic GH release through simultaneous GHRH receptor and ghrelin receptor activation. Studies have investigated this combination effect on GH amplitude, IGF-1 levels, and metabolic parameters. The pulsatile release profile is also of interest in research on GH receptor sensitivity and desensitisation.
| SKU | ONX-CJC1295ND-2 |
|---|---|
| Purity | 99%+ |
| Molecular weight | 3367.90 Da |
| Molecular formula | C152H252N44O42 |
| CAS number | 446036-97-1 |
| Amino-acid sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Amino-acid count | 29 |
| Appearance | White to off-white lyophilised powder |
| Solubility | Reconstitutes in bacteriostatic water |
| Storage | Store at 2–8 °C, protected from light |
| Shelf life | 36 months at 2–8 °C |
Research relevance
- Studied as a modified GRF(1–29) analog of growth-hormone-releasing hormone
- Investigated for stimulation of pituitary GH and downstream IGF-1 secretion
- Examined for short-acting, pulse-preserving GH-release dynamics
Published references
Related research notes
References are provided for scientific background only. They describe preclinical and laboratory research and do not constitute medical, therapeutic, or efficacy claims. This product is sold strictly for research use.
What is CJC-1295 no DAC?
CJC-1295 without DAC (also known as Modified GRF 1-29 or Mod GRF) is a synthetic analogue of growth hormone-releasing hormone comprising the first 29 amino acids of GHRH with four substitutions to improve metabolic stability. Unlike the DAC variant, this form has a half-life of approximately 30 minutes.
Where can a laboratory buy CJC-1295 no DAC in the EU?
Onyx Peptides supplies CJC-1295 no DAC for laboratory research across the European Union. We are operated by Vexio j. s. a. (IČO 54214530) in Slovakia and dispatch from within the EU, so there is no customs entry, no import duty and no border hold. Orders placed before 16:00 CET ship the same day, and shipping is free above €100.
How do I verify the batch of CJC-1295 no DAC I receive?
Each vial carries a batch number. Ask us for the Certificate of Analysis of the batch currently in stock — before you order, not after — and check that the batch number on the certificate matches the one printed on the vial. The analysis is performed by Janoshik Analytical, an independent laboratory in Prague, which will confirm a report it issued if you contact them with its identifier.
How is purity verified?
Every batch is independently tested by Janoshik Analytical using HPLC and Mass Spectrometry. A batch-specific Certificate of Analysis — also covering endotoxins and heavy metals — is available on request.
How fast is delivery?
We dispatch from within the EU, same day on orders placed before 16:00 CET. EU delivery typically takes 1–3 business days.
What payment methods do you accept?
We accept bank transfer (SEPA), including SEPA instant payments which usually arrive within seconds. Your order ships as soon as the transfer clears.
How should this be stored?
Store at 2–8 °C, protected from light. Once reconstituted, keep refrigerated and use within 30 days.
What is the intended use?
All products are supplied strictly for in-vitro laboratory and research use only. They are not for human consumption, veterinary, or clinical use.
