Research Notes
Laboratory reference articles on peptide handling, purity verification, storage and what the published literature reports. Written for researchers, not consumers.
Why Peptide Names Look Like That
BPC-157, GHK-Cu, Semaglutide, MOTS-c, SNAP-8 — five naming systems in five names, each carrying different information.
Read article → October 15, 2026Why Peptides Are Not Orally Bioavailable
Three obstacles in series: gastric acid and pepsin, pancreatic proteases, and an epithelium sealed by tight junctions. Each one alone would be enough.
Read article → October 14, 2026Peptide vs Protein: Where Is the Line?
The 50-residue convention is arbitrary, but it tracks something real — the point where chains fold, and where chemical synthesis stops being the sensible route.
Read article → October 13, 2026Disulfide Bonds and Cyclic Peptides
The only covalent cross-link that forms spontaneously — and the reason some sequences are far harder to make, verify and store than their length suggests.
Read article → October 12, 2026Fridge, Freezer or Shelf: Choosing a Peptide Storage Temperature
Four options with four different costs. Which is right depends on whether the peptide is lyophilised and how long it has to last.
Read article → October 9, 2026Batch Numbers: Why a COA Without One Proves Nothing
A batch number is the least interesting thing on a vial and the one that makes every other quality claim checkable.
Read article → October 8, 2026Heavy Metals Testing in Research Peptides
Elemental impurities come from reagents, catalysts and equipment. Whether the test matters depends entirely on the protocol.
Read article → October 7, 2026ESI vs MALDI: Mass Spectrometry for Peptide Identity
HPLC says how much of one thing is present. Mass spectrometry says what it is — and on a long peptide that is the more important question.
Read article → October 6, 2026How to Read an HPLC Chromatogram on a Peptide COA
The purity percentage is one number derived from the trace. The trace shows how it was arrived at, and whether it should be believed.
Read article → October 5, 2026How Peptides Are Engineered to Last Longer
Native peptides survive minutes. Modern analogues survive days. A small, recognisable set of chemical strategies closes that gap.
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