GHK-Cu 50mg
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper complex) is a naturally occurring tripeptide with a strong affinity for copper(II) ions. First isolated from human plasma in 1973, GHK-Cu levels decline significantly with age, sparking research into its role in tissue homeostasis and regenerative processes.
Extensive in-vitro studies have documented GHK-Cu involvement in extracellular matrix remodelling, including stimulation of collagen and glycosaminoglycan synthesis, as well as regulation of matrix metalloproteinases (MMPs). The peptide has also been studied for its effects on gene expression, with research suggesting it can modulate the activity of over 4,000 human genes.
GHK-Cu research spans multiple domains including dermal biology (skin remodelling, follicular signaling), wound repair, and antioxidant defense mechanisms. Its copper-binding properties are central to its biological activity, as copper is a cofactor for numerous enzymes involved in tissue maintenance.
| SKU | ONX-GHK-CU-50 |
|---|---|
| Purity | 99%+ |
| Molecular weight | 401.91 Da |
| Molecular formula | C14H22CuN6O4 |
| CAS number | 89030-95-5 |
| Amino-acid sequence | GHK |
| Amino-acid count | 3 |
| Appearance | White to off-white lyophilised powder |
| Solubility | Reconstitutes in bacteriostatic water |
| Storage | Store at 2–8 °C, protected from light |
| Shelf life | 36 months at 2–8 °C |
Research relevance
- Studied as a copper-binding tripeptide modulating extracellular-matrix remodelling
- Investigated for its influence on collagen and glycosaminoglycan synthesis
- Examined for broad modulation of gene expression in skin-regeneration models
- Studied in contexts related to antioxidant and anti-inflammatory signalling
- Investigated for copper-ion delivery to cellular metalloenzymes
Published references
Related research notes
References are provided for scientific background only. They describe preclinical and laboratory research and do not constitute medical, therapeutic, or efficacy claims. This product is sold strictly for research use.
What is GHK-Cu?
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper complex) is a naturally occurring tripeptide with a strong affinity for copper(II) ions. First isolated from human plasma in 1973, GHK-Cu levels decline significantly with age, sparking research into its role in tissue homeostasis and regenerative processes.
Where can a laboratory buy GHK-Cu in the EU?
Onyx Peptides supplies GHK-Cu for laboratory research across the European Union. We are operated by Vexio j. s. a. (IČO 54214530) in Slovakia and dispatch from within the EU, so there is no customs entry, no import duty and no border hold. Orders placed before 16:00 CET ship the same day, and shipping is free above €100.
How do I verify the batch of GHK-Cu I receive?
Each vial carries a batch number. Ask us for the Certificate of Analysis of the batch currently in stock — before you order, not after — and check that the batch number on the certificate matches the one printed on the vial. The analysis is performed by Janoshik Analytical, an independent laboratory in Prague, which will confirm a report it issued if you contact them with its identifier.
How is purity verified?
Every batch is independently tested by Janoshik Analytical using HPLC and Mass Spectrometry. A batch-specific Certificate of Analysis — also covering endotoxins and heavy metals — is available on request.
How fast is delivery?
We dispatch from within the EU, same day on orders placed before 16:00 CET. EU delivery typically takes 1–3 business days.
What payment methods do you accept?
We accept bank transfer (SEPA), including SEPA instant payments which usually arrive within seconds. Your order ships as soon as the transfer clears.
How should this be stored?
Store at 2–8 °C, protected from light. Once reconstituted, keep refrigerated and use within 30 days.
What is the intended use?
All products are supplied strictly for in-vitro laboratory and research use only. They are not for human consumption, veterinary, or clinical use.
