Note di ricerca
Laboratory reference articles on peptide handling, purity verification, storage and what the published literature reports. Written for researchers, not consumers.
Freeze-Thaw Damage and Why Aliquoting Solves It
A peptide passing through a freeze does not experience cold. It experiences high concentration at a shifted pH against an ice interface.
Read article → 16/09/2026Solid-Phase Peptide Synthesis, Explained
Merrifield's method explains most of what appears on a certificate of analysis: deletion sequences, why purity falls with length, and why price scales the way it does.
Read article → 15/09/2026Endotoxin in Research Peptides: What It Is and When to Test
Endotoxin does not appear on an HPLC trace and survives autoclaving. For cell-based work it can bias results on the exact pathway being measured.
Read article → 14/09/2026Why Research Peptides Are Lyophilised (And What That Means for Shipping)
Freeze-drying removes the water that drives hydrolysis and oxidation. It is also why cold-chain shipping claims for lyophilised powder do not hold up.
Read article → 11/09/2026Peptide Aggregation: Why It Happens and How to Prevent It
Aggregation is the failure mode that leaves no visible trace. What drives it, which sequences are at risk, and the handling rules that actually prevent it.
Read article → 10/09/2026Insulin Syringe Units Explained: U-100, U-50 and U-40
A unit is not a volume, it depends on the syringe. Plus where measurement error lives and why 10 to 30 units is the target range.
Read article → 9/09/2026Peptide Content vs Purity: Why a 5 mg Vial Is Not 5 mg of Peptide
Purity is a ratio and content is a mass. Counter-ions and residual water take up the difference, and for quantitative work it matters.
Read article → 8/09/2026Reading a Peptide Sequence: Notation, Direction and What It Tells You
One-letter and three-letter codes, why direction matters, and the four things a sequence tells you before any database lookup.
Read article → 7/09/2026SNAP-8: Reproducing a Toxin Mechanism Without the Toxin
An octapeptide modelled on SNAP-25, designed to compete for a place in the SNARE complex rather than cleave it.
Read article → 4/09/2026Glutathione: The Tripeptide With an Unusual Bond
Present at millimolar concentrations, joined by a gamma-peptide bond, and best understood as a redox buffer rather than a signal.
Read article →