KPV 10mg
KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). Despite its small size, KPV has attracted significant research attention for its potent anti-inflammatory properties.
In preclinical studies, KPV has been investigated for its ability to modulate inflammatory signaling pathways, particularly through inhibition of NF-κB nuclear translocation. This mechanism is central to the inflammatory cascade, making KPV a valuable tool for studying immune regulation at the molecular level.
Research has explored KPV across multiple inflammatory models including gastrointestinal, dermal, and systemic inflammation. Studies in colitis models have shown particular promise, with KPV demonstrating the ability to reduce inflammatory markers and support mucosal integrity. Its small molecular size also makes it an interesting candidate for topical and oral delivery route research.
| SKU | ONX-KPV-10 |
|---|---|
| Purity | 99%+ |
| Molecular weight | 342.43 Da |
| Molecular formula | C16H30N4O4 |
| CAS number | 67727-97-3 |
| Amino-acid sequence | KPV |
| Amino-acid count | 3 |
| Appearance | White to off-white lyophilised powder |
| Solubility | Reconstitutes in bacteriostatic water |
| Storage | Store at 2–8 °C, protected from light |
| Shelf life | 36 months at 2–8 °C |
Research relevance
- Studied as the C-terminal tripeptide of α-MSH with anti-inflammatory signalling
- Investigated for modulation of the NF-κB inflammatory pathway
- Examined in preclinical models of intestinal and mucosal inflammation
- Studied in melanocortin-receptor research contexts
Published references
Related research notes
References are provided for scientific background only. They describe preclinical and laboratory research and do not constitute medical, therapeutic, or efficacy claims. This product is sold strictly for research use.
What is KPV?
KPV is a naturally occurring tripeptide (Lys-Pro-Val) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). Despite its small size, KPV has attracted significant research attention for its potent anti-inflammatory properties.
Where can a laboratory buy KPV in the EU?
Onyx Peptides supplies KPV for laboratory research across the European Union. We are operated by Vexio j. s. a. (IČO 54214530) in Slovakia and dispatch from within the EU, so there is no customs entry, no import duty and no border hold. Orders placed before 16:00 CET ship the same day, and shipping is free above €100.
How do I verify the batch of KPV I receive?
Each vial carries a batch number. Ask us for the Certificate of Analysis of the batch currently in stock — before you order, not after — and check that the batch number on the certificate matches the one printed on the vial. The analysis is performed by Janoshik Analytical, an independent laboratory in Prague, which will confirm a report it issued if you contact them with its identifier.
How is purity verified?
Every batch is independently tested by Janoshik Analytical using HPLC and Mass Spectrometry. A batch-specific Certificate of Analysis — also covering endotoxins and heavy metals — is available on request.
How fast is delivery?
We dispatch from within the EU, same day on orders placed before 16:00 CET. EU delivery typically takes 1–3 business days.
What payment methods do you accept?
We accept bank transfer (SEPA), including SEPA instant payments which usually arrive within seconds. Your order ships as soon as the transfer clears.
How should this be stored?
Store at 2–8 °C, protected from light. Once reconstituted, keep refrigerated and use within 30 days.
What is the intended use?
All products are supplied strictly for in-vitro laboratory and research use only. They are not for human consumption, veterinary, or clinical use.
